What Is Homozygous Familial
Hypercholesterolemia (HoFH)?

Homozygous Familial Hypercholesterolemia (HoFH) is the most severe form of inherited high cholesterol, occurring when a child inherits a faulty gene from both parents. Affecting roughly 1 in 250,000 to 1 in 360,000 people, HoFH can cause life-threatening cardiovascular disease in childhood if left untreated.